BioMed Research International / 2015 / Article / Tab 2

Review Article

Big Data Analytics in Healthcare

Table 2

Summary of popular methods and toolkits with their applications.

Toolkit name Category Selected applications

Onto-Express [139, 140] Pathway analysis Breast cancer [141]
GoMiner [142] Pathway analysis Pancreatic cancer [143]
ClueGo [144] Pathway analysis Colorectal tumors [145]
GSEA [146] Pathway analysis Diabetes [147]
Pathway-Express [148] Pathway analysis Leukemia [149]
Recon 2 [150] Reconstruction of metabolic networks Drug target prediction studies [151]
Boolean methods [135, 152, 153] Reconstruction of gene regulatory networks Cardiac differentiation [154]
ODE models [155158] Reconstruction of gene regulatory networks Cardiac development [158]

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.