A Functional Variant at miR-520a Binding Site in PIK3CA Alters Susceptibility to Colorectal Cancer in a Chinese Han Population

Table 1

General characteristics of colorectal cancer cases and controls.

	Cases ()		Controls ()
Age (mean ± SD), years	60.1 ± 12.3		60.7 ± 12.9		0.506
Gender
Male	216	56.0%	229	58.1%	0.563
Female	170	44.0%	165	41.9%
Smoking
Never	262	67.9%	276	70.1%	0.536
Ever	124	32.1%	118	29.9
Family history of cancer
No	332	86.0%	360	91.4%	0.023
Yes	54	14.0%	34	8.6%
Tumor site
Colon	212	54.9%
Rectum	174	45.1%
Tumor stages
I	38	9.8%
II	173	44.8%
III	135	35.0%
IV	40	10.4%