Research Article

Cardiopulmonary Response to Exercise in COPD and Overweight Patients: Relationship between Unloaded Cycling and Maximal Oxygen Uptake Profiles

Table 1

Morphological characteristics, physiological data at rest, and oxygen uptake at the different epochs of exercise. Asterisks denote significant variations compared to controls (; ; and ). For pulmonary function, values in brackets are the percentage of predicted normal data.

Controls COPDsOverweight subjects
HypoxemicNormoxemic

Number18141219
Age, y
Body mass index, kg·m−2
Forced vital capacity (FVC),
lBTPS (% predicted)
  
(101%)
  
(68%)
  
(70%)
  
(97%)
Expiratory reserve volume (ERV), lBTPS
Total lung capacity (TLC),
lBTPS (% predicted)
  
(102%)
  
(100%)
  
(75%)
  
(78%)
Forced expiratory volume in 1 s (FEV1), lBTPS (% predicted)  
(96%)
  
(60%)
  
(81%)
  
(86%)
FEV1/FVC, %86678479
PaO28567***72*85
SpO2, %
Heart rate, min−1
Minute ventilation (VE),
lBTPS·min−1
11111013
Respiratory frequency (fR), min−116181517
Oxygen uptake (VO2),
mlSTPD−1·kg−1
VO2 rest
VO2 end unloaded cycling
VO2 threshold