Research Article
Study of Cytotoxic Effects of Benzonitrile Pesticides
Table 1
The inhibition coefficients (%) for 24 h exposure and (%) for 48 h exposure of benzonitrile pesticides and their microbial metabolic products on Hep G2 cells for concentrations 25 mg/L, 50 mg/L, and 100 mg/L.
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BRX: 3,5-dibromo-4-hydroxybenzonitrile, BRAC: 3,5-dibromo-4-hydroxybenzoic acid, BRAM: 3,5-dibromo-4-hydroxybenzamide, DCB: 2,6-dichlorobenzonitrile, DCBA: 2,6-dichlorobenzoic acid, BAM: 2,6-dichlorobenzamide, CHX: 3,5-dichloro-4-hydroxybenzonitrile, CHXAC: 3,5-dichloro-4-hydroxybenzoic acid, CHXAM: 3,5-dichloro-4-hydroxybenzamide, IOX: 3,5-diiodo-4-hydroxybenzonitrile, IOXAC: 3,5-diiodo-4-hydroxybenzoic acid, and IOXAM: 3,5-diiodo-4-hydroxybenzamide; ND: below detection limit; : the solubility of DCB in water is around 20 mg/L; therefore the inhibitions at concentrations 50 and 100 mg/L are only indicative; ±: standard deviation of 3 parallels. |