Research Article

Breast Cancer by Age at Diagnosis in the Gharbiah, Egypt, Population-Based Registry Compared to the United States Surveillance, Epidemiology, and End Results Program, 2004–2008

Table 3

Age stratified average incidence rates by country of residence and breast cancer characteristics, Egypt’s GCR, and US SEER cases, 2004–2008.

VariableIncidence rate per 100,000 woman-years (95% confidence interval)
25–39 years of age40–54 years of age≥55 years of age

RegistryEgypt’s GCRUS SEER Egypt’s GCRUS SEER Egypt’s GCRUS SEER

Grade
 Low (I/II)17.4 (15.7–19.2)11.9 (11.6–12.3)76.5 (72.3–80.9)95.2 (94.3–96.1)91.2 (85.3–97.4)221.4 (220.1–222.7)
 High (III/IV) 2.3 (1.7–3.0)17.9 (17.5–18.3) 8.2 (6.9–9.7)68.5 (67.7–69.3)11.8 (9.7–14.1)104.7 (103.8–105.6)

Hormone Receptor
 Positive10.3 (9.0–11.7)19.4 (19.0–19.8)45.2 (42.0–48.5)125.9 (124.9–127.0)56.4 (51.8–61.3)268.3 (266.8–269.7)
 Negative 2.8 (2.1–3.5)10.2 (9.9–10.5)13.8 (12.1–15.7) 38.4 (37.9–39.0)16.0 (13.6–18.7) 58.9 (58.2–59.6)

Histology
 Other 6.3 (5.3–7.4) 6.6 (6.3–6.8)29.8 (27.2–32.6) 47.6 (47.0–48.3) 40.5 (36.6–44.7)117.7 (116.7–118.6)
 Duct, NOS19.5 (17.7–21.4)25.6 (25.1–26.1)84.1 (79.8–88.7)130.0 (128.9–131.0)107.0 (100.6–113.7)245.9 (244.5–247.3)

AJCC stage group
 I0.9 (0.6–1.4) 8.6 (8.4–8.9) 4.6 (3.6–5.7)73.0 (72.2–73.8) 5.3 (3.9–6.9)174.9 (173.7–176.1)
 II7.5 (6.4–8.7)13.8 (13.4–14.1)37.7 (34.8–40.8)63.6 (62.8–64.3)42.2 (38.2–46.5)105.4 (104.5–106.3)
 III9.8 (8.6–11.2) 6.1 (5.9–6.3)40.3 (37.3–43.5)24.4 (24.0–24.9)49.6 (45.2–54.2) 36.9 (36.4–37.5)
 IV2.4 (1.8–3.1) 1.8 (1.7–2.0) 9.2 (7.8–10.8) 7.5 (7.2–7.7)18.0 (15.4–20.8) 19.5 (19.1–19.9)

Racea
 White30.0 (29.4–30.6)171.3 (169.9–172.7)350.1 (348.3–351.9)
 Black34.6 (33.1–36.2)163.9 (160.6–167.3)312.3 (307.4–317.4)
 AI/AN14.8 (11.9–18.3)81.6 (74.3–89.5)155.9 (144.1–168.4)
 API27.5 (26.1–29.0)152.0 (148.4–155.7)232.6 (227.9–237.3)

Hispanic 23.5 (22.6–24.5)125.8 (123.2–128.4)238.9 (234.7–243.2)
Non-Hispanic32.5 (31.8–33.1)176.6 (175.2–177.9)347.8 (346.0–349.5)

Total25.7 (23.7–27.9)32.2 (31.7–32.7)113.9 (108.8–119.2)177.6 (176.4–178.8)147.5 (139.9–155.4)363.5 (361.8–365.2)

AI/AN: American Indian/Alaska Native; API: Asian/Pacific Islander; stat cannot calculate other/unknown category incidence rates; —: race/ethnicity unavailable in GCR.