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BioMed Research International

BioMed Research International / 2015 / Article / Tab 2

Research Article

TOP2A Amplification and Overexpression in Hepatocellular Carcinoma Tissues

Table 2

Clinicopathological features of HCC patients ( = 40).
Patients (%)
Age (years) 
 <5018 (45.0)
 ≥5022 (55.0)
 Range35–94
 Mean52.5
 Median51
Sex 
 Male35 (87.5)
 Female5 (12.5)
HBsAg 
 Negative12 (30.0)
 Positive28 (70.0)
AFP 
 <500 ng/mL24 (60.0)
 ≥500 ng/mL13 (32.5)
 Unknown3 (7.5)
Tumor size 
 <5 cm14 (35.0)
 ≥5 cm26 (65.0)
TP53 expression 
 Negative21 (52.5)
 Positive18 (45.0)
 Unknown1 (2.5)
Ki-67 expression 
 <10%9 (22.5)
 ≥10%30 (75.0)
 Unknown1 (2.5)
HBsAg: hepatitis B surface antigen; AFP: alpha fetoprotein; HCC: hepatocellular carcinoma; TP53: tumor protein p53.