Analysis of Monocytic and Granulocytic Myeloid-Derived Suppressor Cells Subsets in Patients with Hepatitis C Virus Infection and Their Clinical Significance

Figure 1

Phenotypic analysis of MDSCs subsets in patients with HCV infection. PBMCs were obtained from patients () and healthy control (). Fluorochrome-labeled antibodies targeting CD33, HLA-DR, CD15, CD14, and CD11b or the appropriate isotype controls were used to stained MDSCs. Then, MDSCs levels were evaluated by flow cytometry. (a) Flow cytometry analysis was performed with gates set on CD14⁺HLA- cells populations (M-MDSCs). (b) Flow cytometry analysis was performed with gates set on HLA-CD33⁺CD11b⁺CD15⁺ cells populations (G-MDSCs).

(a) M-MDSCs

(b) G-MDSCs