Table 1: Literature review of antibiotic cement nail cases.

First authorYearNumber of casesAnatomical siteMean age (range)Follow-up (range)Nail formulation
per 40 g PMMA
Results

Case series
Kanakaris [28]20142414 femurs
10 tibias
47 (17–75) years19 (8–36) months0.5 g gentamicin
2 g vancomycin, antifungals
4% recurrence
5% failure in nail removal
Asloum [29]2014283 femurs
25 tibias
43 (19–70) years48 (4–96) monthsUnknown7% recurrence
7% complications
Dhanasekhar [30]201318Femurs and tibiasUnknownUnknown2 g vancomycin
0.5 gentamicin
0% recurrence
Wasko [23]20131010 tibias42 (20–59) years72 (60–84) months2.5 gentamicin0% recurrence
0% complications
Selhi [31]2011168 femurs
7 tibias
1 humerus
38 (18–54) yearsUnknown4 g vancomycin
0.5 gentamicin
31% recurrence
0% complications
Kanakaris [32]201188 femurs40 (22–76) years12 (12–20) months0.5 g gentamicin
2 g vancomycin
0% recurrence
0% complications
Bar-On [33]201042 femurs
2 tibias
9 (5–14) years41 (36–46) monthsUnknown0% recurrence
50% wound healing disturbances
Bhadra [13]200930Lower limb 47 (20–79) years26 (4–40) months1.2 mg tobramycin
1 g vancomycin
Unknown
Shyam [34]20092523 femurs
2 tibias
33 (21–58) years29 (18–40) months2 g vancomycin
2 g gentamicin
20% recurrence
0% complications
Sancineto [27]2008184 femurs
14 tibias
37 (18–52) years12 (10–54) months4 g vancomycin
Various others
6% recurrence
6% intolerance to nail
Qiang [35]2007195 femurs
14 tibias
38 (22–78) years16 (6–28) months2 g vancomycin0% recurrence
5% complications
Paley [21]200296 femurs
2 tibias
1 humerus
30 (8–70) years41 (32–48) months2.4 tobramycin
2 g vancomycin
0% recurrence
10% rod fracture

Case reports
Mauffrey [36]201411 femur58 years2 months0.5 gentamicin
2.4 g tobramycin
2 g vancomycin
Unknown
Riel [37]201011 tibia ±65 yearsUnknown0.5 g gentamicinUnknown
Madanagopal [12]200411 tibiaUnknownUnknown1.2 g tobramycin0% recurrence
Ohtsuka [38]200211 tibia28 years18 months1.2 gentamicin0% recurrence