Research Article

Evaluation of Liver Fibrosis Using Texture Analysis on Combined-Contrast-Enhanced Magnetic Resonance Images at 3.0T

Table 3

Receiver operating characteristics (texture versus Metavir).

Classification Cutoff Area under curveSensitivitySpecificityAccuracy

F <1 versus F ≥11.8050.814 [0.654 0.975]0.659 [0.513 0.804]0.800 [0.449 1.000]0.674 [0.524 0.797]
F <2 versus F ≥21.9160.889 [0.783 0.994] 0.895 [0.757 1.000]0.778 [0.621 0.919]0.826 [0.686 0.916]
F <3 versus F ≥32.0600.862 [0.701 1.000]0.778 [0.506 1.000]0.784 [0.651 0.916]0.783 [0.615 0.867]
F <4 versus F = 42.1740.976 [0.855 1.000]1.000 [0.907 1.000]0.930 [0.854 1.000]0.935 [0.788 0.974]

Cutoff: the operating point on the ROC curve closest to (), the point of maximum sensitivity and specificity. —95% confidence interval. The mismatch between the texture-based cutoff and the histologic classification threshold is expected (see text).