Applying NGS Data to Find Evolutionary Network Biomarkers from the Early and Late Stages of Hepatocellular Carcinoma

Table 4

Top 30 proteins of total-stage liver cancer.

Protein	CRV	value	Case_AvgExp	Control_AvgExp
APP	81.53	<	14385	14041	0.03
ELAVL1		0.000187	1757	1319	0.41
CCDC33		0.000464	3	1	1.7
UBC	25.19	0.000588	35625	35490	0.01
HIST3H3	24.3	0.000626	1	1	0.02
KRTAP10-1	23.96	0.000643	1	1	0.02
ESR1	23.79	0.000652	236	1537	−2.7
UBD	23.34	0.000682	14701	1781	3.04
H2AFX	17.28	0.001125	705	271	1.38
KRTAP10-5	17.05	0.001133	1	1	0.05
HGS	15.2	0.001329	2473	1167	1.08
TRAF2	14.28	0.001461	581	277	1.07
HSP90AB1	14.16	0.001483	29756	14629	1.02
PCNA	13.58	0.001572	1962	904	1.12
SMARCA4	13.21	0.001611	2546	1115	1.19
TAF6	12.84	0.001636	1075	478	1.17
SUMO2	12.6	0.001704	2968	2112	0.49
UBQLN4	12.59	0.001713	1881	905	1.05
COPS5	12.45	0.001743	1604	1184	0.44
CEP250	12.41	0.001747	673	268	1.33
EZH2	12.15	0.001802	351	49	2.84
CDK1	11.69	0.001892	462	34	3.78
TCF3	11.35	0.00199	980	415	1.24
CDC20	11.28	0.002011	519	20	4.7
MCM2	10.9	0.002126	1220	174	2.81
GRB2	10.64	0.002233	3488	2608	0.42
WHSC1	10.5	0.002288	1291	447	1.53
MYOD1	10.5	0.002292	2	1	1.22
AURKB	10.48	0.002305	169	14	3.61
SUMO1	10.36	0.002373	2520	2982	−0.24