Research Article

Antioxidant, Hepatoprotective Potential and Chemical Profiling of Propolis Ethanolic Extract from Kashmir Himalaya Region Using UHPLC-DAD-QToF-MS

Table 3

Effect of different doses of propolis on serum parameters in INH-RIF induced hepatotoxicity.

AST (IU/L)ALT (IU/L)ALP (IU/L)T.bil (mg/dL)TP (gm/dL)CHL (gm/dL)TG (gm/dL)

Group I145.9 ± 3.391166.5 ± 2.939339.9 ± 3.3040.845 ± 0.3858.260 ± 0.44970.75 ± 3.15457.98 ± 2.297
Group II303.4 ± 3.65359.7 ± 3.26515.3 ± 2.192.017 ± 0.494.713 ± 0.16271.4 ± 4.33165.3 ± 3.03
Group III176.9 ± 3.58205.6 ± 2.80379.6 ± 3.741.103 ± 0.046.468 ± 0.17107.1 ± 3.0393.31 ± 2.40
Group IV234.2 ± 3.34271.7 ± 3.03445.4 ± 3.731.690 ± 0.026.125 ± 0.21195.0 ± 3.51151.8 ± 3.43
Group V290.1 ± 2.95341.2 ± 2.73498.0 ± 3.521.830 ± 0.044.263 ± 0.87256.0 ± 3.58158.4 ± 2.86

Values are mean ± S.E.M; = 6; , toxic versus normal, , extract treated groups versus toxic, , extract treated groups versus toxic, and , extract treated groups versus toxic; ns, not significant.