Antioxidant, Hepatoprotective Potential and Chemical Profiling of Propolis Ethanolic Extract from Kashmir Himalaya Region Using UHPLC-DAD-QToF-MS
Table 3
Effect of different doses of propolis on serum parameters in INH-RIF induced hepatotoxicity.
AST (IU/L)
ALT (IU/L)
ALP (IU/L)
T.bil (mg/dL)
TP (gm/dL)
CHL (gm/dL)
TG (gm/dL)
Group I
145.9 ± 3.391
166.5 ± 2.939
339.9 ± 3.304
0.845 ± 0.385
8.260 ± 0.449
70.75 ± 3.154
57.98 ± 2.297
Group II
303.4 ± 3.65
359.7 ± 3.26
515.3 ± 2.19
2.017 ± 0.49
4.713 ± 0.16
271.4 ± 4.33
165.3 ± 3.03
Group III
176.9 ± 3.58
205.6 ± 2.80
379.6 ± 3.74
1.103 ± 0.04
6.468 ± 0.17
107.1 ± 3.03
93.31 ± 2.40
Group IV
234.2 ± 3.34
271.7 ± 3.03
445.4 ± 3.73
1.690 ± 0.02
6.125 ± 0.21
195.0 ± 3.51
151.8 ± 3.43
Group V
290.1 ± 2.95
341.2 ± 2.73
498.0 ± 3.52
1.830 ± 0.04
4.263 ± 0.87
256.0 ± 3.58
158.4 ± 2.86
Values are mean ± S.E.M; = 6; , toxic versus normal, , extract treated groups versus toxic, , extract treated groups versus toxic, and , extract treated groups versus toxic; ns, not significant.