Antidepressant-Like Effect of the Leaves of Pseudospondias microcarpa in Mice: Evidence for the Involvement of the Serotoninergic System, NMDA Receptor Complex, and Nitric Oxide Pathway

Figure 7

Effect of joint administration of D-serine (DS) or D-cycloserine (DCS) and PME, fluoxetine (FLX), or desipramine (DES) on the total duration of immobility in the TST in mice. The values represent means ± SEM of 5 mice. ; versus vehicle-treated animals (one-way ANOVA followed by Newman-Keuls’ test). Significant difference between treatments: ; (two-way ANOVA followed by Bonferroni’s test).

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