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BioMed Research International
Volume 2015 (2015), Article ID 401509, 10 pages
http://dx.doi.org/10.1155/2015/401509
Research Article

Immunodiagnosis of Canine Visceral Leishmaniasis Using Mimotope Peptides Selected from Phage Displayed Combinatorial Libraries

1Departamento de Parasitologia, ICB, Universidade Federal de Minas Gerais, CP 486, Belo Horizonte 31270-901, MG, Brazil
2Departamento Bioquímica e Imunologia, ICB, Universidade Federal de Minas Gerais, CP 486, Belo Horizonte 31270-901, MG, Brazil
3SysDiag CNRS-BioRad UMR 3145, Cap Delta/Parc Euromédecine, 1682 rue de la Valsière, CS 61003, 34184 Montpellier Cedex 4, France
4Departamento de Análises Clínicas, Escola de Farmácia, Universidade Federal de Ouro Preto, Ouro Preto 35400-000, MG, Brazil
5Escola de Veterinária, Universidade Federal de Minas Gerais, CP 486, Belo Horizonte 31270-901, MG, Brazil

Received 17 November 2014; Revised 27 December 2014; Accepted 11 January 2015

Academic Editor: Mehdi Chenik

Copyright © 2015 Christina Monerat Toledo-Machado et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. Gramiccia and L. Gradoni, “The current status of zoonotic leishmaniases and approaches to disease control,” International Journal for Parasitology, vol. 35, no. 11-12, pp. 1169–1180, 2005. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Moreno and J. Alvar, “Canine leishmaniasis: epidemiological risk and the experimental model,” Trends in Parasitology, vol. 18, no. 9, pp. 399–405, 2002. View at Publisher · View at Google Scholar · View at Scopus
  3. P. Desjeux, “Focus: leishmaniasis,” Nature Reviews Microbiology, vol. 2, no. 9, pp. 692–693, 2004. View at Publisher · View at Google Scholar
  4. F. Mancianti, F. Pedonese, and A. Poli, “Evaluation of dot enzyme-linked immunosorbent assay (dot-ELISA) for the serodiagnosis of canine leishmaniosis as compared with indirect immunofluorescence assay,” Veterinary Parasitology, vol. 65, no. 1-2, pp. 1–9, 1996. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Cabral, J. E. O'Grady, S. Gomes, J. C. Sousa, H. Thompson, and J. Alexander, “The immunology of canine leishmaniosis: strong evidence for a developing disease spectrum from asymptomatic dogs,” Veterinary Parasitology, vol. 76, no. 3, pp. 173–180, 1998. View at Publisher · View at Google Scholar · View at Scopus
  6. V. Sideris, G. Papadopoulou, E. Dotsika, and E. Karagouni, “Asymptomatic canine leishmaniasis in Greater Athens area, Greece,” European Journal of Epidemiology, vol. 15, no. 3, pp. 271–276, 1999. View at Publisher · View at Google Scholar · View at Scopus
  7. A. Moshfe, M. Mohebali, E. Afshoun et al., “Canine visceral leishmaniasis in boyer ahmad district, kohgiluyeh & boyer ahmad province, Southwest of Iran,” Iranian Journal of Parasitology, vol. 7, no. 4, pp. 75–81, 2012. View at Google Scholar · View at Scopus
  8. R. Fisa, C. Riera, M. Gállego, J. Manubens, and M. Portús, “Nested PCR for diagnosis of canine leishmaniosis in peripheral blood, lymph node and bone marrow aspirates,” Veterinary Parasitology, vol. 99, no. 2, pp. 105–111, 2001. View at Publisher · View at Google Scholar · View at Scopus
  9. R. B. Tesh, “Control of zoonotic visceral leishmaniasis: is it time to change strategies?” American Journal of Tropical Medicine and Hygiene, vol. 52, no. 3, pp. 287–292, 1995. View at Google Scholar · View at Scopus
  10. Ministério da Saúde, Manual de Vigilância e Controle da Leishmaniose Visceral, Ministério da Saúde, São Paulo, Brazil, 2006.
  11. W. A. Alves and P. D. Bevilacqua, “Quality of diagnosis of canine visceral leishmaniasis in epidemiological surveys: an epidemic in Belo Horizonte, Minas Gerais, Brazil, 1993–1997,” Cadernos de Saúde Pública, vol. 20, no. 1, pp. 259–265, 2004. View at Publisher · View at Google Scholar · View at Scopus
  12. E. S. Silva, C. M. F. Gontijo, and M. N. Melo, “Contribution of molecular techniques to the epidemiology of neotropical Leishmania species,” Trends in Parasitology, vol. 21, no. 12, pp. 550–552, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. G. Matlashewski, B. Arana, A. Kroeger et al., “Visceral leishmaniasis: elimination with existing interventions,” The Lancet Infectious Diseases, vol. 11, no. 4, pp. 322–325, 2011. View at Publisher · View at Google Scholar · View at Scopus
  14. O. Noya, M. E. Patarroyo, F. Guzmán, and B. A. de Noya, “Immunodiagnosis of parasitic diseases with synthetic peptides,” Current Protein and Peptide Science, vol. 4, no. 4, pp. 299–308, 2003. View at Publisher · View at Google Scholar · View at Scopus
  15. G. P. Smith, “Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface,” Science, vol. 228, no. 4705, pp. 1315–1317, 1985. View at Publisher · View at Google Scholar · View at Scopus
  16. J. K. Scott and G. P. Smith, “Searching for peptide ligands with an epitope library,” Science, vol. 249, no. 4967, pp. 386–390, 1990. View at Publisher · View at Google Scholar · View at Scopus
  17. K. Manoutcharian, A. Díaz-Orea, G. Gevorkian et al., “Recombinant bacteriophage-based multiepitope vaccine against Taenia solium pig cysticercosis,” Veterinary Immunology and Immunopathology, vol. 99, no. 1-2, pp. 11–24, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. R. Lanzillotti and T. L. Coetzer, “Phage display: a useful tool for malaria research?” Trends in Parasitology, vol. 24, no. 1, pp. 18–23, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. R. C. R. Hell, P. Amim, H. M. de Andrade et al., “Immunodiagnosis of human neurocysticercosis using a synthetic peptide selected by phage-display,” Clinical Immunology, vol. 131, no. 1, pp. 129–138, 2009. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Z. Troncarelli, J. B. Camargo, J. G. Machado, S. B. Lucheis, and H. Langoni, “Leishmania spp. and/or Trypanosoma cruzi diagnosis in dogs from endemic and nonendemic areas for canine visceral leishmaniasis,” Veterinary Parasitology, vol. 164, no. 2–4, pp. 118–123, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. M. M. Bradford, “A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding,” Analytical Biochemistry, vol. 72, no. 1-2, pp. 248–254, 1976. View at Publisher · View at Google Scholar · View at Scopus
  22. P. L. Ey, S. J. Prowse, and C. R. Jenkin, “Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-sepharose,” Immunochemistry, vol. 15, no. 7, pp. 429–436, 1978. View at Publisher · View at Google Scholar · View at Scopus
  23. L. L. C. Bonnycastle, J. S. Mehroke, M. Rashed, X. Gong, and J. K. Scott, “Probing the basis of antibody reactivity with a panel of constrained peptide libraries displayed by filamentous phage,” Journal of Molecular Biology, vol. 258, no. 5, pp. 747–762, 1996. View at Publisher · View at Google Scholar · View at Scopus
  24. G. Ferrières, S. Villard, M. Pugnière et al., “Affinity for the cognate monoclonal antibody of synthetic peptides derived from selection by phage display. Role of sequences flanking the binding motif,” European Journal of Biochemistry, vol. 267, no. 6, pp. 1819–1829, 2000. View at Publisher · View at Google Scholar · View at Scopus
  25. F. Sanger, S. Nicklen, and A. R. Coulson, “DNA sequencing with chain-terminating inhibitors,” Proceedings of the National Academy of Sciences of the United States of America, vol. 74, no. 12, pp. 5463–5467, 1977. View at Publisher · View at Google Scholar · View at Scopus
  26. H. Gausepohl, C. Boulin, M. Kraft, and R. W. Frank, “Automated multiple peptide synthesis,” Peptide Research, vol. 5, no. 6, pp. 315–320, 1992. View at Google Scholar · View at Scopus
  27. R. A. M. de Avila, S. Stransky, M. Velloso et al., “Mimotopes of mutalysin-II from Lachesis muta snake venom induce hemorrhage inhibitory antibodies upon vaccination of rabbits,” Peptides, vol. 32, no. 8, pp. 1640–1646, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. E. Harlow and D. Lane, Antibodies: A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA, 1988.
  29. H. M. Geysen, S. J. Rodda, and T. J. Mason, “A priori delineation of a peptide which mimics a discontinuous antigenic determinant,” Molecular Immunology, vol. 23, no. 7, pp. 709–715, 1986. View at Publisher · View at Google Scholar · View at Scopus
  30. J. L. Fleiss, R. L. Spitzer, J. Endicott, and J. Cohen, “Quantification of agreement in multiple psychiatric diagnosis,” Archives of General Psychiatry, vol. 26, no. 2, pp. 168–171, 1972. View at Publisher · View at Google Scholar · View at Scopus
  31. S. D. Walter, “Properties of the summary receiver operating characteristic (SROC) curve for diagnostic test data,” Statistics in Medicine, vol. 21, no. 9, pp. 1237–1256, 2002. View at Publisher · View at Google Scholar · View at Scopus
  32. M. F. Znette, V. M. Lima, M. D. Laurenti et al., “Serological cross-reactivity of Trypanosoma cruzi, Ehrlichia canis, Toxoplasma gondii, Neospora caninum and Babesia canis to Leishmania infantum chagasi tests in dogs,” Revista da Sociedade Brasileira de Medicina Tropical, vol. 47, no. 1, pp. 105–107, 2014. View at Publisher · View at Google Scholar
  33. S. Sundar and M. Rai, “Laboratory diagnosis of visceral leishmaniasis,” Clinical and Diagnostic Laboratory Immunology, vol. 9, no. 5, pp. 951–958, 2002. View at Publisher · View at Google Scholar · View at Scopus
  34. M. M. Costa, M. Penido, M. S. Santos et al., “Improved canine and human visceral leishmaniasis immunodiagnosis using combinations of synthetic peptides in enzyme-linked immunosorbent assay,” PLoS Neglected Tropical Diseases, vol. 6, no. 5, Article ID e1622, 2012. View at Publisher · View at Google Scholar · View at Scopus
  35. D. Menezes-Souza, T. A. de Oliveira Mendes, A. C. de Araújo Leão, M. de Souza Gomes, R. T. Fujiwara, and D. C. Bartholomeu, “Linear B-cell epitope mapping of MAPK3 and MAPK4 from Leishmania braziliensis: implications for the serodiagnosis of human and canine leishmaniasis,” Applied Microbiology and Biotechnology, 2014. View at Publisher · View at Google Scholar
  36. D. Menezes-Souza, T. A. Mendes, S. Gomes Mde et al., “Epitope mapping of the HSP83.1 protein of Leishmania braziliensis discloses novel targets for immunodiagnosis of tegumentary and visceral clinical forms of leishmaniasis,” Clinical and Vaccine Immunology, vol. 21, no. 7, pp. 949–959, 2014. View at Publisher · View at Google Scholar
  37. D. Menezes-Souza, T. A. Mendes, R. A. Nagem et al., “Mapping B-cell epitopes for the peroxidoxin of Leishmania (Viannia) braziliensis and its potential for the clinical diagnosis of tegumentary and visceral leishmaniasis,” PLoS ONE, vol. 9, no. 6, Article ID e99216, 2014. View at Publisher · View at Google Scholar
  38. D. A. D. Silva, M. D. F. Madeira, T. R. Abrantes, C. J. D. L. B. Filho, and F. B. Figueiredo, “Assessment of serological tests for the diagnosis of canine visceral leishmaniasis,” Veterinary Journal, vol. 195, no. 2, pp. 252–253, 2013. View at Publisher · View at Google Scholar · View at Scopus
  39. Z. Maia, M. Lírio, S. Mistro, C. M. C. Mendes, S. R. Mehta, and R. Badaro, “Comparative study of rK39 Leishmania antigen for serodiagnosis of visceral leishmaniasis: systematic review with meta-analysis,” PLoS Neglected Tropical Diseases, vol. 6, no. 1, Article ID e1484, 2012. View at Publisher · View at Google Scholar · View at Scopus
  40. J. Ramos-Jesus, K. A. Carvalho, R. A. S. Fonseca et al., “A piezoelectric immunosensor for Leishmania chagasi antibodies in canine serum,” Analytical and Bioanalytical Chemistry, vol. 401, no. 3, pp. 917–925, 2011. View at Publisher · View at Google Scholar · View at Scopus