The Oncofetal Protein IMP3: A Novel Grading Tool and Predictor of Poor Clinical Outcome in Human Gliomas

Figure 5

(a) Ki67 labeling index was scored in HGGs as the percentage of positive tumor cells in each case. AO: anaplastic oligodendroglioma; AA: anaplastic astrocytoma; GBM: glioblastoma. by -test. (b) ROC curve was used to calculate a cut-off for patients’ categorization according to Ki67 levels ( index). Disease-free survival (, HR = 0.4, 95% CI: 0.2–0.9) (c) and overall survival (, HR = 0.4, 95% CI: 0.1–1.1) (d); end-points were evaluated in GBM patients according to Ki67 index using the Kaplan-Meier method. values are from log-rank test.

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