Positive Association of Vitamin D Receptor Gene Variations with Multiple Sclerosis in South East Iranian Population

Table 2

Genotype and allele frequencies of TaqI (rs731236) and ApaI (rs7975232).

SNP	Genotype/allele	Patients	Controls	Odds ratio	value	Power study
				(95% CI)		(%)
TaqI (rs731236)	TT, (%)	9 (8)	94 (77)	1		100
	TC, (%)	44 (39)	26 (21.4)	17.7 (7.6–40.9)	<0.0001	80.54
	CC, (%)	60 (53)	2 (1.6)	313 (65.5–1500)	<0.0001	100
	T, (%)	62 (27.4)	214 (87.7)	1
	C, (%)	164 (72.6)	30 (12.3)	18.9 (11.6–30.3)	<0.0001	100
ApaI (rs7975232)	AA	40 (35.4)	61 (50)	1		56.61
	AC	62 (54.9)	56 (45.9)	1.7 (1–2.9)	0.056	23.34
	CC	11 (9.7)	5 (4.1)	3.4 (1.1–10.4)	0.036	29.81
	A	142 (62.8)	178 (73)	1
	C	84 (37.2)	66 (27)	1.6 (1.1–2.4)	0.019	32.77

TaqI genotypes (TT = wild type; TC = heterozygote; CC = mutant type); ApaI genotypes (AA = wild type; AC = heterozygote; CC = mutant type).