Research Article
Predictors for Early Identification of Hepatitis C Virus Infection
Table 1
Comparison of demographic characteristics and clinical measurements in the HCV-infected group and in the negative control group.
| | Variable | HCV-infected group
( = 144) | Negative control group
( = 168) | -test
| ANCOVA
|
| | Gender (%) | | | | | | Male | 83 (57.6) | 38 (22.6) | | | | Female | 61 (42.4) | 130 (77.4) | <0.001 | | | Age mean (sd) | 39.3 ± 10.8 | 37.4 ± 7.3 | 0.071 | | | WBC (×103l) | 6.8 ± 1.9 | 6.0 ± 1.7 | <0.001 | 0.006 | | RBC (×106l) | 4.9 ± 0.7 | 4.5 ± 0.5 | <0.001 | 0.024 | | HB (g/dl) | 14.7 ± 1.5 | 13.4 ± 1.8 | <0.001 | <0.001 | | HCT (%) | 43.0 ± 3.9 | 39.8 ± 4.4 | <0.001 | 0.001 | | MCV (fl) | 89.1 ± 8.0 | 88.1 ± 6.3 | 0.243 | 0.122 | | MCH (pg) | 30.5 ± 3.1 | 29.6 ± 2.8 | 0.008 | 0.030 | | MCHC (g/dl) | 34.2 ± 1.0 | 33.5 ± 1.3 | <0.001 | 0.005 | | PLT (×103) | 222.3 ± 58.8 | 270.5 ± 61.8 | <0.001 | <0.001 | | NEU (%) | 56.4 ± 9.0 | 58.3 ± 8.2 | 0.052 | <0.001 | | LYM (%) | 34.0 ± 8.2 | 33.1 ± 7.7 | 0.270 | 0.648 | | MONO (%) | 6.6 ± 1.8 | 5.7 ± 1.4 | <0.001 | <0.001 | | EOS (%) | 2.5 ± 1.6 | 2.4 ± 1.7 | 0.630 | 0.174 | | BAS (%) | 0.5 ± 0.3 | 0.5 ± 0.3 | 0.140 | 0.230 | | RDW-SD (fl) | 41.8 ± 2.9 | 42.6 ± 2.9 | 0.013 | 0.055 | | RDW-CV (%) | 13.3 ± 1.5 | 13.6 ± 1.5 | 0.040 | 0.034 | | PDW (fl) | 13.2 ± 2.0 | 12.1 ± 1.9 | <0.001 | <0.001 | | MPV (fl) | 10.8 ± 0.8 | 10.5 ± 0.9 | <0.001 | 0.001 | | P-LCR (%) | 31.7 ± 6.2 | 28.5 ± 6.4 | <0.001 | <0.001 | | PCT (%) | 0.2 ± 0.1 | 0.3 ± 0.1 | <0.001 | <0.001 | | NEUT (×103l) | 3.9 ± 1.4 | 3.6 ± 1.3 | 0.034 | 0.090 | | LYMPH (×103l) | 2.3 ± 0.7 | 1.9 ± 0.6 | <0.001 | 0.004 | | MONO (×103l) | 0.4 ± 0.1 | 0.3 ± 0.1 | <0.001 | <0.001 | | EOS (×103l) | 0.2 ± 0.1 | 0.1 ± 0.1 | 0.083 | 0.561 | | BAS (×103l) | 0.03 ± 0.02 | 0.03 ± 0.02 | 0.463 | 0.789 | | TPO (pg/ml) | 74.4 ± 66.3 | 42.0 ± 37.9 | <0.001 | <0.001 | | ALT (IU/L) | 35.5 ± 45.0 | 23.3 ± 29.5 | 0.006 | 0.339 |
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HCV: hepatitis C virus; ANCOVA: analysis of covariance; WBC: white blood cell count; RBC: red blood cell count; Hb: haemoglobin; HCT: haematocrit; MCV: mean corpuscular volume; MCH: mean corpuscular haemoglobin; MCHC: mean corpuscular haemoglobin concentration; RDW: RBC distribution width; PLT: platelet count; PCT: plateletcrit; PDW: platelet distribution width; MPV: mean platelet volume; P-LCR: platelet-large cell ratio; NEU: neutrophil; LYM: lymphocyte; MON: monocyte; EOS: eosinophil; BAS: basophil; TPO: thrombopoietin; ALT: alanine aminotransferase.
Significance level: < 0.05.
Age- and gender-adjusted value.
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