Mechanical Stress Promotes Cisplatin-Induced Hepatocellular Carcinoma Cell Death

Figure 5

Different carnosine : CisPt molar ratios cytotoxic effect on HepG2 cells for 24 hours as per MTT assay. The data are presented as a mean of at least three independent experiments (mean ± SD). Left to right: Media = control HepG2 cells. Car : Cis 1 : 1 = HepG2 cells exposed to CisPt 8 μg/mL and carnosine in 1 : 1 molar ratio. Car : Cis 1.5 : 1 = HepG2 cells exposed to CisPt 8 μg/mL and carnosine in 1.5 : 1 molar ratio. Car : Cis 2 : 1 = HepG2 cells exposed to CisPt 8 μg/mL and carnosine in 2 : 1 molar ratio. Car : Cis 2.5 : 1 = HepG2 cells exposed to CisPt 8 μg/mL and carnosine in 2.5 : 1 molar ratio. Car : Cis 3 : 1 = HepG2 cells exposed to CisPt 8 μg/mL and carnosine in 3 : 1 molar ratio (error bars represent the standard deviation). The values shown are the values of the mean of every condition as compared to the control cells ().