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BioMed Research International
Volume 2015, Article ID 434516, 7 pages
Clinical Study

Relationship between Sum of the Four Limbs’ Pulse Pressure and Brachial-Ankle Pulse Wave Velocity and Atherosclerosis Risk Factors in Chinese Adults

1The Chinese PLA General Hospital Health Science Center, FuXing Road 28, Beijing 100853, China
2Institute of Geriatric Cardiology, General Hospital of Chinese PLA, Beijing 100853, China
3Department of Geriatric Endocrinology, PLA General Hospital, Beijing 100853, China

Received 27 July 2014; Accepted 14 October 2014

Academic Editor: Maciej Banach

Copyright © 2015 Yansong Zheng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The aim of the present study was to analyze the relationship between the sum of the four limbs’ pulse pressure (Sum-PP) and brachial-ankle pulse wave velocity (baPWV) and atherosclerosis risk factors and evaluate the feasibility of Sum-PP in diagnosing atherosclerosis systemically. For the purpose, a cross-sectional study was conducted on the basis of medical information of 20748 adults who had a health examination in our hospital. Both Sum-PP and baPWV exhibited significant variations among different human populations grouped by gender, smoking, drinking, and age. Interestingly, Sum-PP had similar varying tendency with baPWV in different populations. And further study in different populations showed that Sum-PP was significantly positively related to baPWV. We also investigated the relationship between Sum-PP, baPWV, and cardiovascular risk factors, respectively. We found that both Sum-PP and baPWV had significant positive correlation with atherosclerosis risk factors while both of them were negatively related to HDL-c. In addition, there was a significant close correlation between Sum-PP and baPWV in the whole population (, ). Thus, Sum-PP is closely related to baPWV and is of important value for clinical diagnosis of atherosclerosis.