BioMed Research International / 2015 / Article / Tab 2

Research Article

High Order Gene-Gene Interactions in Eight Single Nucleotide Polymorphisms of Renin-Angiotensin System Genes for Hypertension Association Study

Table 2

Single-locus analysis of eight SNPs for hypertension and nonhypertension groups.

LociGenotypesHT ()Non-HT ()P values

AGT gene
 T174M
  (rs4762)
CC243 (77.6%)106 (81.5%)
CT64 (20.4%)21 (16.2%)0.303
TT6 (1.9%)3 (2.3%)0.874
C : T7.2 : 18.6 : 1
 M235T
  (rs699)
CC220 (70.3%)92 (70.8%)
CT84 (26.8%)38 (29.2%)0.734
TT9 (2.9%)0 (0.0%)
C : T5.1 : 15.8 : 1
 G-6A
  (rs5051)
AA213 (68.1%)90 (69.2%)
AG88 (28.1%)40 (30.8%)0.749
GG12 (3.8%)0 (0.0%)
A : G4.6 : 15.5 : 1
 A-20C
  (rs5050)
AA295 (94.2%)125 (96.2%)
AC15 (4.8%)3 (2.3%)0.232
CC3 (1.0%)2 (1.5%)0.619
A : C28.8 : 136.1 : 1
 G-152A
  (rs11568020)
GG289 (92.3%)120 (92.3%)
GA21 (6.7%)10 (7.7%)0.589
AA3 (1.0%)0 (0.0%)
G : A22.2 : 125.0 : 1
 G-217A
  (rs5049)
GG228 (72.8%)102 (78.5%)
GA64 (20.4%)25 (19.2%)0.608
AA21 (6.7%)3 (2.3%)0.057
G : A4.9 : 17.4 : 1
ACE gene
 I/D
  (rs4646994)
II103 (32.9%)27 (20.8%)
ID146 (46.6%)67 (51.5%)0.031
DD64 (20.4%)36 (27.7%)0.010
I : D1.3 : 10.9 : 1
AT1R gene
 A1166C
  (rs5186)
AA287 (91.7%)115 (88.5%)
AC25 (8.0%)14 (10.8%)0.339
CC1 (0.3%)1 (0.8%)0.505
A : C22.215.3 : 1

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19.