A Comparison of Variant Calling Pipelines Using Genome in a Bottle as a Reference

<div>Sensitivity as a function of depth for the top aligner and top variant caller. (a) Results for the depth of every SNV plotted against sensitivity for the top aligner, BWA mem, paired with every variant caller. (b) Results for the depth of every SNV plotted against sensitivity for the top variant caller, GATK UnifiedGenotyper, paired with every aligner.</div>

BioMed Research International

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Figure 3

Figure 3: A Comparison of Variant Calling Pipelines Using Genome in a Bottle as a Reference 