Activation of Endocannabinoid System Is Associated with Persistent Inflammation in Human Aortic Aneurysm

Figure 5

Expression of matrix metalloproteinases and their tissue inhibitors in aortic aneurysm. The mRNA expression of (a) matrix metalloproteinase- (MMP-) 1, (b) MMP-2, (c) MMP-9, and (d) MMP-14 was not significantly different in aorta from patients with aneurysm of the ascending aorta (AAA) compared to coronary artery disease (CAD) except for MMP-2. The mRNA expression of (e) tissue inhibitor of matrix metalloproteinase- (TIMP-) 1, (f) TIMP-2, and (g) TIMP-4 was not significantly different in aorta from patients with AAA compared to CAD except for TIMP-4. (h) Ratios of different MMP/TIMP showed only a significant difference for MMP-2/TIMP-4 between AAA and CAD group. in the AAA group and in the CAD RT-qPCR group. mRNA expression in RT-qPCR is related to controls and GAPDH using comparative ΔΔCt method. Bracket indicates .

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