Research Article

An Upgrade on the Rabbit Model of Anthracycline-Induced Cardiomyopathy: Shorter Protocol, Reduced Mortality, and Higher Incidence of Overt Dilated Cardiomyopathy

Table 3

Scores for grade and extension of histopathological lesions in the heart.

GroupLesion gradeLesion extension

DOX22.65 ± 0.391.65 ± 0.44
DAU32.63 ± 0.432.68 ± 0.47
DAU42.76 ± 0.323.18 ± 0.43

Data expressed as mean ± SEM. Statistical significance is at p < 0.05; compared to DOX2; #compared to DAU3.