BioMed Research International / 2015 / Article / Fig 1

Research Article

Proteolytic Disassembly of Viral Outer Capsid Proteins Is Crucial for Reovirus-Mediated Type-I Interferon Induction in Both Reovirus-Susceptible and Reovirus-Refractory Tumor Cells

Figure 1

Reovirus-mediated induction of IFN-β and Noxa in tumor cells. (a), (b) Dose-dependent induction of IFN-β and Noxa expression by reovirus. qRT-PCR analysis was used to measure mRNA levels of IFN-β and Noxa 24 hrs after infection. The data were normalized by the data of the mock group. The data shown represent the mean ± SD of triplicate measurements.

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