Applications of lipopeptides in medical field.
|Microorganisms ||Biosurfactant type|| Activity/application |
|Bacillus subtilis MZ-7 and B. amyloliquefaciens ES-2|| Surfactin ||Antimicrobial and antifungal activities [32–35]; inhibition of fibrin clot formation ; hemolysis and formation of ion channels in lipid membranes ; antitumor activity against Ehrlich’s ascites carcinoma cells and antiviral activity against HIV-1 ; high concentration of Surfactin affects the aggregation of amyloid β-peptide into fibrils, a key pathological process associated with Alzheimer’s disease ; antifungal, antiviral, antitumor, insecticidal, and antimycoplasma activities .|
|Bacillus subtilis, B. amyloliquefaciens B128 and B. amyloliquefaciens PPCB004|| Iturin||Antimicrobial activity and antifungal activities against profound mycosis. Effect on the morphology and membrane structure of yeast cells . Increase in the electrical conductance of bimolecular lipid membranes and acting as nontoxic and nonpyrogenic immunological adjuvant .|
|Bacillus subtilis ||Iturin and Surfactin||Both bioagents show broad hypocholesterolemic activities  and can act as antibiotics, antiviral, and antitumor agents; immuno-modulators; specific toxins; and enzyme inhibitors .|