BioMed Research International / 2015 / Article / Tab 3 / Research Article
Oxygen Transport in a Three-Dimensional Microvascular Network Incorporated with Early Tumour Growth and Preexisting Vessel Cooption: Numerical Simulation Study Table 3 Parameter values used in the simulation.
Parameter Value Description Reference 10 μ m Lattice constant 0.82 Average osmotic reflection coefficient for plasma proteins Baxter and Jain (1989) [19 ] 20 mmHg Colloid osmotic pressure of plasma Baxter and Jain (1989) [19 ] 15 mmHg Colloid osmotic pressure of interstitial fluid Baxter and Jain (1989) [19 ] 4.13 × 10−8 cm2 /mmHg s
Hydraulic conductivity coefficient of the interstitium Baxter and Jain (1989) [19 ] /200 cm−1 Surface area per unit volume for transport in the interstitium Baxter and Jain (1989) [19 ] 10−9 cm2 s−1 MDE diffusion coefficient Anderson (2005) [14 ] 1.3 × 102 cm3 M−1 s−1 ECM degradation coefficient Cai et al. (2011) [17 ] 1.7 × 10−18 Mcells−1 s−1 MDE production by TC Cai et al. (2011) [17 ] 0.3 × 10−18 Mcells−1 s−1 MDE production by EC Cai et al. (2011) [17 ] 1.7 × 10−8 s−1 MDE decay coefficient Anderson (2005) [14 ] 1.27 × 10−15 μ mol/(μ m3 mmHg) Bunsen solubility coefficient Fang et al. (2008) [20 ] 10−5 cm2 s−1 Oxygen diffusion coefficient Anderson (2005) [14 ] 6.25 × 10−17 Mcells−1 s−1 Oxygen consumption coefficient Anderson (2005) [14 ] 2.8 × 10−7 cm/mmHg s
Vessel permeability in tumour tissue Baxter and Jain (1989) [19 ] 6.5 mmHg Vessel compliance coefficient Netti et al. (1996) [21 ] 0.1 Vessel compliance index Netti et al. (1996) [21 ]