The Mechanism of Melanocytes-Specific Cytotoxicity Induced by Phenol Compounds Having a Prooxidant Effect, relating to the Appearance of Leukoderma

Figure 11

High performance liquid chromatography (HPLC) analysis of rhododendrol (RD). After 100.0 μM RD was added to 100.0 units/mL tyrosinase, the sample mixture was incubated for (a) 0, (b) 1.5, and (c) 30 min at 37°C and injected into the reverse-phase HPLC. The separated peaks were monitored at 310 nm.

(a) 0 min

(b) 1.5 min

(c) 30 min