Layer 5 Pyramidal Neurons’ Dendritic Remodeling and Increased Microglial Density in Primary Motor Cortex in a Murine Model of Facial Paralysis

Figure 1

Experimental preparation and design. (a) Lateral view of a mouse’s head, schematizing facial nerve branches innervating face muscles; the branches transected during irreversible nerve lesion surgery, as well as the approximate place where they were cut, are indicated by scissors. T, temporal; Z, zygomatic; B, buccal; and M, mandibular branches of VII facial nerve. (b) Schema of the experimental design showing its time line and indicating the color representing each group (white for sham, light gray for 1 week, and black for 3 weeks after facial nerve lesion).

(a)

(b)