Clinical Study

Effect of Spirulina Intervention on Oxidative Stress, Antioxidant Status, and Lipid Profile in Chronic Obstructive Pulmonary Disease Patients

Table 6

Comparison between the effects of the 2 doses of spirulina on serum content of oxidants and antioxidants and on the activity of burst enzymes in COPD patients.

Parameters After 30 days After 60 days
Change in percentage (%) at (500 × 2) mg doseChange in percentage (%) at (500 × 4) mg doseChange in percentage (%) at (500 × 2) mg doseChange in percentage (%) at (500 × 4) mg dose

Malondialdehyde (MDA) (nmoL/mL)12.1717.7220.8935.71
Lipid hydroperoxide (nmoL/mL)6.0614.623.1432.78
Catalase (kU/L)5.7114.67.9333.97
Superoxide dismutase (SOD) (U/mL)4.9811.0812.8420.19
Glutathione-S-transferase (GST) (U/mL)2.5711.268.9415.73
Glutathione (GSH) (nmoL/mL)8.2313.4219.0827.67
Vitamin C (mg/dL)9.2111.8421.0528.94
Cholesterol (mg/dL)3.037.149.0515.84
Triglyceride (TG) (mg/dL)1.483.252.856.24
High density lipoprotein (HDL) (mg/dL)1.22.262.945.88