Evaluation of Single-Impact-Induced Cartilage Degeneration by Optical Coherence Tomography

Table 3

Quantitative OCT parameter values as a function of time (preimpaction; postimpaction; after 1 day; after 4 days; after 8 days) in response to three different impact energies. Data are presented as M ± SD; ; statistical differences were assessed using nonparametric Kruskal-Wallis test to assess differences between individual time points [tp] and groups [gr], respectively. Dunn’s post hoc testing revealed significant differences (bold) primarily between time points (# 1–9), while differences between impact modalities were found for postimpact, OII only. Here, pairwise comparison revealed only MIMP versus HIMP to be different (). Consecutive numbers indicate posttest details as found in Table 4. Data are presented as M ± SD; . Table legend is as in Table 2.

		Controls	LIMP	MIMP	HIMP	value (gr)
OII	Preimpact	7.395 ± 2.684; 10	7.492 ± 1.762; 8	5.596 ± 2.200; 8	5.279 ± 1.496; 8	0.059
	Postimpact	7.660 ± 1.983; 10	7.817 ± 1.252; 8	8.099 ± 5.112; 8	10.14 ± 1.693; 8	0.039 ()
	Day 1	7.567 ± 2.211; 8	7.836 ± 1.629; 6	6.613 ± 3.908; 6	9.788 ± 1.454; 6	0.088
	Day 4	6.739 ± 1.502; 6	7.861 ± 2.218; 4	6.708 ± 6.261; 4	8.814 ± 0.786; 4	0.274
	Day 8	6.721 ± 1.576; 4	7.040 ± 3.737; 2	4.644 ± 0.002; 2	9.496 ± 0.148; 2	0.400
	value (tp)	0.846	0.992	0.903	<0.001 (1)
OHI	Preimpact	2.190 ± 0.33; 10	2.110 ± 0.227; 8	2.121 ± 0.57; 8	2.224 ± 0.207; 8	0.873
	Postimpact	2.272 ± 0.419; 10	2.222 ± 0.27; 8	2.225 ± 0.505; 8	1.971 ± 0.251; 8	0.203
	Day 1	1.274 ± 0.288; 8	1.210 ± 0.218; 6	1.162 ± 0.341; 6	1.054 ± 0.116; 6	0.441
	Day 4	1.366 ± 0.322; 6	1.364 ± 0.121; 4	1.175 ± 0.305; 4	1.135 ± 0.199; 4	0.460
	Day 8	1.270 ± 0.298; 4	1.473 ± 0.104; 2	1.221 ± 0.300; 2	1.016 ± 0.044; 2	0.519
	value (tp)	<0.001 (2)	<0.001 (3)	0.003 (4)	<0.001 (5)
OAI	Preimpact	59.9 ± 27.6; 10	63.2 ± 33.4; 8	79.6 ± 68.4; 8	77.3 ± 19.0; 8	0.535
	Postimpact	67.2 ± 29.9; 10	69.8 ± 39.1; 8	81.3 ± 60.8; 8	69.2 ± 25.4; 8	0.985
	Day 1	149.7 ± 38.3; 8	177.3 ± 9.8; 6	172.5 ± 42.4; 6	164.1 ± 16.2; 6	0.461
	Day 4	168.0 ± 41.2; 6	159.5 ± 36.1; 4	192.2 ± 42.3; 4	155.4 ± 18.4; 4	0.517
	Day 8	151.8 ± 39.4; 4	132.2 ± 51.5; 2	199.2 ± 7.8; 2	155.5 ± 18.1; 2	0.454
	value (tp)	<0.001 (6)	0.002 (7)	0.018 (8)	<0.001 (9)