[Retracted] Lentivirus-Mediated siRNA Targeting ER-α Inhibits Tumorigenesis and Induces Apoptosis in Hepatocarcinoma Cells

Figure 2

Effect of ER-α knockdown on cell proliferation. Hep3B and HCCLM3 cells were infected with ER-α siRNA, nonsilencing siRNA (NS siRNA), or lentivirus (LV). Cells untreated served as control. After 0, 24, 48, or 72 hours of incubation, cell viability was performed by MTT assay (a); a cell proliferation assay was done by counting cell number at 1, 3, 5, and 7 days after infection (b); a soft agar colony formation assay was carried out 14 days after infection to assess the growth ability of cells (c). Compared with other groups, , .

(a)

(b)

(c)