Osteopontin Involves Cisplatin Resistance and Poor Prognosis in Oral Squamous Cell Carcinoma

Figure 1

Immunostaining for OPN expression in OSCC patient samples. (a) The representative case of OSCC shows absence of OPN immunoreactivity (400x magnification). (b) The representative case of OSCC shows positive of OPN immunoreactivity in the cytoplasm of the neoplastic squamous epithelial cells (200x magnification). (c) Adjacent noncancerous tissue showed no OPN expression. (d) Statistical analysis showed that OPN expression levels in OSCC sample significantly correlated with gender, stage, N stage, and smoking.

(a)

(b)

(c)

(d)