Osteopontin Involves Cisplatin Resistance and Poor Prognosis in Oral Squamous Cell Carcinoma

Table 4

Correlation between the clinicopathological features and 5-year overall survival in oral squamous cell carcinoma.

Variables	Number of patients	Cumulative 5-year overall survival rate		HR (95% CI)
Age
60	102	31.0%	0.628
60	19	26.3%
Gender
Male	117	29.4%	0.415
Female	4	50.0%
Stage
IVa	35	64.5%	<0.001	1
IVb	86	15.3%		3.936 (2.129–7.277)	<0.001
T stage
1-2	28	38.7%	0.488
3-4	93	27.4%
N stage
Negative	40	51.5%	0.002	1
Positive	81	20.5%		2.436 (1.422–4.175)	0.001
Chemotherapy
PF	83	24.7%	0.123
TPF	38	41.0%
Alcohol
Never	30	33.3%	0.538
Yes	91	29.1%
Smoking
Never	29	48.0%	0.010	1
Yes	92	24.4%		1.869 (1.014–3.355)	0.036
Betel nuts
Never	31	33.0%	0.096
Yes	90	29.2%
OPN
Negative	27	53.0%	<0.001	1
Positive	94	23.7%		2.036 (1.080–3.839)	0.028

CI, confidence interval; HR, hazard ratio.
Indicates significantly difference ().