Association of Polymorphisms in X-Ray Repair Cross Complementing 1 Gene and Risk of Esophageal Squamous Cell Carcinoma in a Chinese Population

Table 4

XRCC1 haplotype analysis of three polymorphisms in XRCC1 gene.

Haplotypes	Case N (%)	Control N (%)		OR (95% CI)	P	OR (95% CI)^*	P^*
CGT	323 (42.4)	349 (40.4)	Reference	1.00	—	—	—
TGT	152 (19.9)	189 (21.9)	1.11	0.87 (0.67, 1.13)	0.29	0.81 (0.60, 1.10)	0.18
CAT	221 (29.0)	229 (26.5)	0.12	1.04 (0.82, 1.32)	0.73	0.99 (0.74, 1.31)	0.92
CGC	57 (7.5)	89 (10.3)	3.93	0.69 (0.48, 1.00)	0.05	0.62 (0.40, 0.96)	0.03
CAC	2 (0.3)	4 (0.5)	0.10	0.54 (0.10, 2.97)	0.76	0.25 (0.03, 2.30)	0.22
TAT	3 (0.4)	1 (0.1)	0.33	3.24 (0.34, 31.32)	0.57	3.60 (0.36, 35.79)	0.27
TGC	4 (0.5)	3 (0.3)	0.01	1.44 (0.32, 6.49)	0.92	0.76 (0.10, 5.72)	0.79
TAC	0	—	—	—	—	—	—
Total	762 (100)	864 (100)	—	—	—	—	—

adjusted for age, gender, smoking, drinking, and family history of cancer.
The order of three SNPs: codon 194, codon 399, and −77T>C.