Association of Polymorphisms in X-Ray Repair Cross Complementing 1 Gene and Risk of Esophageal Squamous Cell Carcinoma in a Chinese Population

Table 5

Combination genotypes analysis of XRCC1 codons 194, 399, and −77T>C.

Combined genotypes	Case (%)	Control (%)		OR (95% CI)		OR (95% CI)^*	^*
CC/GG/TT	39 (11.2)	43 (10.6)	Reference	1.00	—	—	—
CT/GA/TT	68 (19.5)	71 (17.6)	0.04	1.06 (0.61, 1.82)	0.85	0.95 (0.53, 1.72)	0.87
CT/GG/TT	65 (18.7)	72 (17.8)	0.00	0.99 (0.58, 1.72)	0.99	0.88 (0.49, 1.60)	0.68
CC/GA/TT	60 (17.2)	66 (16.3)	0.00	1.00 (0.57, 1.75)	0.99	1.02 (0.56, 1.87)	0.95
TT/GG/TT	29 (8.3)	37 (9.2)	0.19	0.86 (0.45, 1.66)	0.66	0.91 (0.45, 1.84)	0.80
CT/GG/CT	16 (4.6)	38 (9.4)	4.35	0.46 (0.22, 0.96)	0.04	0.52 (0.24, 1.13)	0.10
CC/AA/TT	23 (6.6)	23 (5.7)	0.07	1.10 (0.53, 2.27)	0.79	0.86 (0.39, 1.92)	0.72
CC/GA/CT	17 (4.9)	23 (5.7)	0.28	0.81 (0.38, 1.75)	0.60	0.74 (0.32, 1.70)	0.48
CC/GG/CT	20 (5.7)	22 (5.4)	0.00	1.00 (0.48, 2.11)	1.00	1.09 (0.50, 2.42)	0.82
CT/GA/CT	4 (1.1)	2 (0.5)	0.23	2.21 (0.38, 12.71)	0.63	1.18 (0.18, 7.74)	0.86
CC/AA/CT	1 (0.3)	3 (0.7)	0.14	0.37 (0.04, 3.68)	0.71	0.37 (0.04, 3.87)	0.41
CT/AA/TT	3 (0.9)	1 (0.2)	0.31	3.31 (0.33, 33.13)	0.58	3.74 (0.36, 38.83)	0.27
Others	3 (0.9)	3 (0.9)	—	—	—	—	—
Total	348 (100)	404 (100)	—	—	—	—	—

adjusted for age, gender, smoking, drinking, and family history of cancer.