HMGB1-Induced Cross Talk between PTEN and miRs 221/222 in Thyroid Cancer

Figure 6

Effect of HMGB1 on the proliferation rate of parental and transfected CAL62 and BCPAP cells. 10⁵ parental cells and transfectants were seeded into a 6-well plate at time 0 with or without 10 nM HMGB1. At the indicated times cell number and cell viability of each well were counted with a haemocytometer. Data represent the mean values of 3 independent experiments (±SD). versus transfectants and parental cells and versus transfectants and transfectants treated with HMGB1.