Clinical Study
MRI for Assessing Response to Neoadjuvant Therapy in Locally Advanced Rectal Cancer Using DCE-MR and DW-MR Data Sets: A Preliminary Report
Table 3
Volume measures assessed by the three volumetric methods (
(C),
(DCE), and
(DWI)).
| | Tool | All () | Responders () | Nonresponders () | p value |
| | (C) | | | | | | Pre-CRT [cm3] | 36.9 ± 34.4 | 30.6 ± 22.6 | 38.4 ± 26.6 | | | Post-CRT [cm3] | 16.7 ± 8.8 | 12.4 ± 6.9 | 20.6 ± 9.5 | | | Volume change [%] | 44.5 ± 43.0 | 60.6 ± 33.2 | 21.7 ± 46.6 | <0.001 | | (DCE) | | | | | | Pre-CRT [cm3] | 30.9 ± 29.1 | 31.4 ± 23.7 | 33.9 ± 25.4 | | | Post-CRT [cm3] | 18.5 ± 8.1 | 11.1 ± 6.7 | 24.7 ± 10.8 | | | Volume change [%] | 33.3 ± 38.4 | 64.0 ± 23.7 | 19.0 ± 36.9 | <0.001 | | (DWI) | | | | | | Pre-CRT [cm3] | 14.6 ± 12.6 | 12.5 ± 10.1 | 15.8 ± 9.3 | | | Post-CRT [cm3] | 9.0 ± 5.1 | 6.4 ± 4.4 | 7.9 ± 5.5 | | | Volume change [%] | 28.3 ± 43.1 | 48.2 ± 30.0 | 21.2 ± 44.0 | <0.001 |
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Note: results are expressed as median value ± standard deviation.
Wilcoxon signed-rank test.
CRT, chemoradiation therapy; (C), conventional T2-weighted volumetry; (DWI), diffusion-weighted imaging volumetry; (DCE), dynamic contrast enhanced volumetry.
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