Figure 3: (a) Hepatic parenchyma altered structure: an expanded portal area is shown, with fibrous septa and hepatocytes enclosed in them. Inflammatory cells and ductular proliferation are seen, with positive Periodic Acid Schiff (PAS) content inside several proliferated biliary ducts. (b) Close-up view of the portal area in which four biliary ducts are seen (3 in the top half of the image and one in the lower half of the image) with PAS positive plugging inside. Images lent by Dr. Daniel Azorín, pathology department.