A Novel Loss-of-Sclerostin Function Mutation in a First Egyptian Family with Sclerosteosis

Figure 2

Proband (on the right hand side of the photo) and his affected brother (on the left hand side of the photo) showing distorted facies and strong body build (a); lateral view of the face of the proband showing proptosis and prognathism (b); both hands of the proband showing bilateral radial deviation of index fingers, camptodactyly of 5th fingers, and soft tissue syndactyly between fingers (c); both feet of the proband showing bilateral broad big toes with wide space between the 1st and 2nd toes, bilateral clinodactyly of 4th and 5th toes, and hypoplastic nails and soft tissue syndactyly between toes (d).

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