Prognosis Relevance of Serum Cytokines in Pancreatic Cancer
Table 3
Prognosis factors in multivariate analysis.
Cytokines
Overall survival
Overall model fit
β
HR
95% CI
value
value
IL-29
0.081
1.084
1.010
1.164
0.026
0.004212
B7-1/CD80
4.351
77.574
1.138
5289.45
0.043
0.002494
PD-ECGF
0.264
1.302
0.944
1.797
0.108
0.001350
EG-VEGF/PK1
0.003
1.003
1.000
1.005
0.049
0.000134
NRG1-beta1/HRG1-beta1
0.020
1.020
0.994
1.047
0.129
0.000286
Cytokines
Overall survival in the univariate analysis
β
HR
95% CI
value
IL-29
0.012
1.012
1.002
1.023
0.021
B7-1/CD80
0.373
1.452
0.876
2.407
0.148
PD-ECGF
0.044
1.045
0.997
1.096
0.068
EG-VEGF/PK1
−0.0001
1.000
0.999
1.000
0.640
NRG1-beta1/HRG1-beta1
−0.004
0.996
0.979
1.014
0.673
β: coefficient provided by the Cox's regression model for a particular patient and cytokine; HR: hazard ratio (represents the factor by which the hazard changes for each one-unit increase of the cytokine expression); 95% CI: upper and lower limits of the confidence interval with a significance level of 0.05.