Table 3: Prognosis factors in multivariate analysis.

CytokinesOverall survivalOverall model fit
βHR95% CI value value

IL-290.0811.0841.0101.1640.0260.004212
B7-1/CD804.35177.5741.1385289.450.0430.002494
PD-ECGF0.2641.3020.9441.7970.1080.001350
EG-VEGF/PK10.0031.0031.0001.0050.0490.000134
NRG1-beta1/HRG1-beta10.0201.0200.9941.0470.1290.000286

CytokinesOverall survival in the univariate analysis
βHR95% CI value

IL-290.012 1.0121.002 1.0230.021
B7-1/CD800.3731.4520.8762.4070.148
PD-ECGF0.0441.0450.9971.0960.068
EG-VEGF/PK1 −0.00011.0000.9991.0000.640
NRG1-beta1/HRG1-beta1−0.0040.9960.9791.0140.673

β: coefficient provided by the Cox's regression model for a particular patient and cytokine; HR: hazard ratio (represents the factor by which the hazard changes for each one-unit increase of the cytokine expression); 95% CI: upper and lower limits of the confidence interval with a significance level of 0.05.