ω-3 PUFAs and Resveratrol Differently Modulate Acute and Chronic Inflammatory Processes

Figure 1

Production of inflammatory mediators by activated PBLs and its modulation by RV, DHA, and EPA. PBLs from healthy individuals were activated with LPS in the presence of the indicated substances (in mol/L) and the inflammatory mediators in supernatants of 24 h cultures were determined in duplicate. The results are expressed as the ratio of substance + LPS-treated cells/LPS-treated cells. Data are given as mean ± SD of experiments obtained from PBL from at least four individuals. The dotted line (at ratio 1) indicates the no-effect level. , ¥ indicate statistically significant differences observed in 50% and >75% of the donors, respectively.