The Impact of LEP G-2548A and LEPR Gln223Arg Polymorphisms on Adiposity, Leptin, and Leptin-Receptor Serum Levels in a Mexican
Mestizo Population
Table 1
Demographic, clinical, and anthropometrics measures in study group according to WHO classification.
Female
Male
Normal range
Overweight
Obese
Normal range
Overweight
Obese
(BMI 18.5–24.9 kg/m2)
(BMI 25.0–29.9 kg/m2)
(BMI ≥ 30 kg/m2)
(BMI 18.5–24.9 kg/m2)
(BMI 25.0–29.9 kg/m2)
(BMI ≥ 30 kg/m2)
Age (years)
33.4 ± 13.72
42.9 ± 12.45
42.8 ± 11.77
<0.00
30.3 ± 12.95
39.6 ± 12.84
41.4 ± 10.10
<0.00
Blood pressure (mmHg)
Diastolic
70 ± 7.6
75 ± 7.3
79 ± 9.4
<0.00
72 ± 9.0
75 ± 8.6
79 ± 9.4
0.02
Systolic
106 ± 9.4
118 ± 13.1
120 ± 17.9
<0.00
115 ± 10.1
117 ± 11.9
122 ± 12.8
NS
Hemoglobin (g/dL)
13.9 ± 1.06
13.6 ± 1.21
14.1 ± 1.00
0.02
16.3 ± 1.15
16.1 ± 1.08
15 ± 1.1
NS
Glucose (mg/dL)
87 ± 13.0
96 ± 11.8
96 ± 15.6
<0.00
87 ± 10.7
96 ± 15.0
103 ± 15.3
<0.00
White blood cells (k/L)
5.8 ± 1.44
6.1 ± 1.29
6.5 ± 1.54
0.00
5.8 ± 1.91
6.3 ± 1.27
7.3 ± 2.04
0.01
Erythrocyte sedimentation rate (mm/h)
17 ± 9.2
23 ± 9.4
24 ± 9.9
<0.00
5 ± 5.8
9 ± 7.5
11 ± 7.0
0.02
C reactive protein (mg/dL)
1.4 ± 1.93
3.9 ± 3.22
4.3 ± 3.30
<0.00
1.1 ± 1.61
2.7 ± 2.59
4.5 ± 4.07
<0.03
Height (cm)
158.9 ± 14.88
157.6 ± 5.95
159.2 ± 8.16
—
173.4 ± 6.07
171.5 ± 6.09
172.5 ± 8.28
—
Weight (kg)
57.8 ± 7.36
68.0 ± 6.14
86.2 ± 12.34
—
67.7 ± 7.19
80.9 ± 7.52
101.2 ± 12.83
—
Body mass index (kg/m2)
22.4 ± 1.61
27.3 ± 1.41
33.9 ± 3.63
—
22.4 ± 1.78
27.4 ± 1.45
34.0 ± 4.21
—
Waist circumference (cm)
76.2 ± 7.61
88.7 ± 6.75
102.7 ± 10.30
<0.001
82.5 ± 7.71
95.8 ± 8.01
110.9 ± 10.55
<0.001
Hip circumference (cm)
96.2 ± 5.89
103.5 ± 4.99
117.4 ± 9.49
<0.001
94.1 ± 6.33
101.3 ± 5.15
113.1 ± 11.15
<0.001
Waist/hip ratio
0.790 ± 0.0604
0.856 ± 0.0647
0.881 ± 0.0843
<0.00
0.871 ± 0.0880
0.946 ± 0.0722
0.990 ± 0.0864
<0.00
Body fat mass (%)
27.2 ± 5.53
36.1 ± 4.10
43.1 ± 3.40
<0.001
15.0 ± 5.18
25.8 ± 4.00
33.6 ± 6.47
<0.001
Skinfold thickness (mm)
Biceps
11.6 ± 4.70
17.4 ± 5.34
23.5 ± 8.16
<0.001
5.2 ± 2.58
9.6 ± 5.11
16.4 ± 7.46
<0.022
Triceps
20.6 ± 4.67
27.4 ± 5.28
33.6 ± 8.57
<0.001
11.7 ± 5.23
16.4 ± 5.94
22.1 ± 7.96
<0.012
Subscapular
20.4 ± 7.90
30.2 ± 6.98
38.8 ± 8.57
<0.001
15.1 ± 6.48
25.3 ± 7.12
37.3 ± 11.18
<0.001
Suprailiac
23.2 ± 6.46
29.9 ± 5.98
35.0 ± 7.74
<0.002
17.4 ± 8.07
26.3 ± 8.43
35.1 ± 9.78
<0.006
mmHg: millimeter of mercury; g: gram; dL: deciliter; kg: kilogram; cm: centimeter; mm: millimeter; m2: square meter. Normal range versus overweight and obese; overweight versus obese; normal range versus obese; k: thousand; L: microlitre.
