Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2015, Article ID 543038, 9 pages
http://dx.doi.org/10.1155/2015/543038
Research Article

Maternal Glucose during Pregnancy and after Delivery in Women with Gestational Diabetes Mellitus on Overweight Status of Their Children

1Tianjin Women’s and Children’s Health Center, Tianjin 300070, China
2Population Cancer Research Program, Dalhousie University, Halifax, NS, Canada B3H 4R2
3Department of Epidemiology, School of Public Health, Tianjin Medical University, Tianjin 300070, China
4Departments of Epidemiology and Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
5Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60208, USA
6Chronic Disease Epidemiology Laboratory, Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA

Received 10 September 2014; Revised 21 November 2014; Accepted 5 December 2014

Academic Editor: Beverly Muhlhausler

Copyright © 2015 Shuang Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. To examine the association of maternal glycemia during pregnancy and after delivery with anthropometry in the offspring of mothers with gestational diabetes mellitus (GDM). Methods. A total of 1,263 GDM mothers and their children finished the health survey at 1–5 years after delivery. Results. Offspring of GDM mothers who were diagnosed with diabetes during pregnancy had higher prevalence of overweight, higher mean weight for height scores, and higher mean BMI for age scores at 1–5 years old than the offspring of GDM mothers who were diagnosed with impaired glucose tolerance (IGT) during pregnancy. Offspring of GDM mothers who developed diabetes 1–5 years after delivery had higher mean values of scores for weight for height and BMI for age at 1–5 years old than the offspring of GDM mothers who had normal glucose or prediabetes after delivery. Conclusions. Offspring of GDM mothers who were diagnosed with diabetes during pregnancy or after delivery had an increased risk of childhood overweight or weight gain at 1–5 years old compared with children of GDM mothers with IGT during pregnancy or with normal glucose or prediabetes after delivery.