BioMed Research International / 2015 / Article / Tab 3

Research Article

The Correlation between miRNA and Lymph Node Metastasis in Gastric Cancer

Table 3

Univariate and multivariate analysis of risk factors of lymph node metastasis in gastric cancer.

Without LNM With LNM  value

(%) 

(%) 
Univariate analysisMultivariate analysis

Age (y/o)0.758
 <659 (39.1)7 (30.4)
 ≧6514 (60.9)16 (69.6)
Gender0.130
 M/F17/611/12
Tumor size (cm)0.236
 <515 (65.2)10 (43.5)
 ≧58 (34.8)13 (56.5)
Tumor location0.767
 Upper third stomach5 (21.7)3 (13.6)
 Middle third stomach9 (39.1)10 (45.5)
 Lower third stomach9 (39.1)9 (40.9)
Lauren’s classification0.071
 Intestinal type17 (52.6)10 (43.5)
 Diffuse type6 (47.4)13 (56.5)
Cell differentiation0.236
 Poor8 (34.8)13 (45.5)
 Moderate/well15 (65.2)10 (56.6)
Stromal reaction type<0.001<0.001
 Medullary7 (30.4)0
 Intermediate16 (69.6)17 (73.9)
 Scirrhous06 (26.1)
Lymphovascular invasion<0.001<0.001
 Absence18 (78.3)5 (21.7)
 Presence5 (21.7)18 (78.3)
Pathological T categories<0.001<0.001
 T111 (47.8)1 (4.3)
 T28 (34.8)4 (17.4)
 T34 (17.4)15 (65.2)
 T403 (13)
Pathological TNM stage<0.001<0.001
 I19 (82.6)0
 II4 (17.4)10 (43.5)
 III07 (30.4)
 IV06 (26.1)
Expression of miR-1207-5p<0.001<0.001
 No change7 (30.4)20 (87)
 Downregulation1 (4.3)1 (4.3)
 Upregulation15 (65.2)2 (8.7)

LNM: lymph node metastasis.