Figure 1: Definition of duplex window. (a) Four scenarios associated with duplex window selection. The solid black dot represents the nucleotides of the known mature miRNA. The hollow circles represent the nucleotides that are not part of the mature miRNA in the pre-miRNA transcript. All boxes represent duplex windows. The black box represents the known miRNA: duplex. The four colored dashed boxes represent four scenarios while defining duplex window. (b)–(e) Detailed schematics corresponding to each scenario.