Review Article
[Retracted] Influence of Two Common Polymorphisms in the EPHX1 Gene on Warfarin Maintenance Dosage: A Meta-Analysis
Table 1
Baseline characteristics and methodological quality of all included studies.
| First author | Year | Country | Ethnicity | Case number | Gender (M/F) | Age (years) | Genotyping method | SNP | NOS score |
|
Özer [20] | 2013 | Turkey | Asians | 107 | 53/54 | 53.9 ± 13.6 | LightSNiP assay | rs2292566 G>A | 6 | Liang [6] | 2013 | China | Asians | 300 | 138/162 | 47.9 ± 12.5 | SNaPshot assay | rs2292566 G>A | 8 | | | | | | | | | rs4653436 A>G | 8 |
Volcik [37] |
2006 | China | Asians | 217 | 90/127 | 51.3 ± 15.0 | DHPLC | rs4653436 A>G | 7 | Ciccacci [21] | 2011 | Italy | Caucasians | 141 | 78/70 | 68.2 | TaqMan | rs2292566 G>A | 6 | | | | | | | | | rs4653436 A>G | 6 | Luo [23] | 2010 | China | Asians | 197 | 82/115 | 52.9 ± 11.8 | Base-quenched probe | rs2292566 G>A | 7 | | | | | | | | | rs4653436 A>G | 7 | Pautas [14] | 2010 | France | Caucasians | 290 | 69/231 | 86.7 ± 6.0 | TaqMan | rs2292566 G>A | 8 | Carlquist [13] | 2010 | USA | Caucasians | 168 | 79/89 | 71.0 ± 13.0 | TaqMan | rs4653436 A>G | 7 |
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M: male; F: female; DHPLC: denaturing high performance liquid chromatography; NOS: Newcastle-Ottawa Scale criteria; SNP: single nucleotide polymorphisms.
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