BioMed Research International / 2015 / Article / Tab 1

Review Article

Influence of Two Common Polymorphisms in the EPHX1 Gene on Warfarin Maintenance Dosage: A Meta-Analysis

Table 1

Baseline characteristics and methodological quality of all included studies.

First authorYearCountryEthnicityCase numberGender (M/F)Age (years)Genotyping methodSNPNOS score

Özer [20]2013TurkeyAsians10753/5453.9 ± 13.6LightSNiP assayrs2292566 G>A6
Liang [6]2013ChinaAsians300138/16247.9 ± 12.5SNaPshot assayrs2292566 G>A8
rs4653436 A>G8
Volcik [37] 2006ChinaAsians21790/12751.3 ± 15.0DHPLCrs4653436 A>G7
Ciccacci [21]2011ItalyCaucasians14178/7068.2TaqManrs2292566 G>A6
rs4653436 A>G6
Luo [23]2010ChinaAsians19782/11552.9 ± 11.8Base-quenched probers2292566 G>A7
rs4653436 A>G7
Pautas [14]2010FranceCaucasians29069/23186.7 ± 6.0TaqManrs2292566 G>A8
Carlquist [13]2010USACaucasians16879/8971.0 ± 13.0TaqManrs4653436 A>G7

M: male; F: female; DHPLC: denaturing high performance liquid chromatography; NOS: Newcastle-Ottawa Scale criteria; SNP: single nucleotide polymorphisms.