Clinical Study

Effect of Teriparatide on Unstable Pertrochanteric Fractures

Table 3

Outcome measures of patients in the control and teriparatide groups at the last follow-up.

ParametersGroup AGroup B value

Variables
 Age at time of operation (yrs)81.0 ± 9.382.1 ± 7.60.254
 Body mass index (kg/m2)21.9 ± 2.522.9 ± 3.10.117
 ASA classification0.464
  ASA I
  ASA II29 (65.9%)18 (62.1%)
  ASA III15 (34.1%)11 (37.9%)
 Hospital stay (day)8.6 ± 1.67.9 ± 1.60.067
 BMD of contralateral hip (-score)−4.0 ± 1.2−3.9 ± 1.00.908
 Follow-up (months)37.3 ± 7.436.2 ± 7.10.650
Subsequent fracture
 Vertebral fracture7 (15.9%)3 (10.3%)0.421
 Hip fracture2 (4.5%)1 (3.4%)0.677
 Wrist fracture2 (4.5%)2 (6.9%)0.494
 Overall subsequent fracture11 (25%)5 (17.2%)0.350
Union time (weeks)14.3 ± 2.811.2 ± 1.6<0.001*
Tip apex distance (mm)19.1 ± 2.618.8 ± 2.40.643
Sliding of lag screw (mm)9.6 ± 5.32.2 ± 1.4<0.001*
Femoral shortening (mm)13.2 ± 7.44.2 ± 2.6<0.001*
Varus collapse (degrees)7.7 ± 4.42.6 ± 1.7<0.001*

Group A: patient without any supplementation of pharmacologic treatment.
Group B: patient treated with teriparatide.
Values are shown as mean (standard deviation) or as the (%).
values for between-group comparison were determined by the chi-squared test and Fisher’s exact test which were used for nominal variables.
Student’s -test was used for parametric variables.
*Statistically significant ( value < 0.05).