Clinical Study

Can Variability of Pattern ERG Signal Help to Detect Retinal Ganglion Cells Dysfunction in Glaucomatous Eyes?

Table 4

Pearson correlation coefficient (CC) and significance level (SL-) in 37 early manifest glaucoma patients.

AgeIOPCCTMDPSDRNFLGCCAmplitudePhaseCV_ampCV_phase
(mmHg)(µm)(dB)(dB)(µm)(µm)(µV)( rad)(%)(%)

AgeCC−0.108−0.1330.0820.0380.1330.051−0.181−0.1280.1260.105
SL-0.5230.4330.6290.8230.4320.7620.2840.4490.4570.536

IOP (mmHg)CC−0.1080.2690.078−0.2520.2960.177−0.251−0.3640.110.362
SL-0.5230.1080.6460.1330.0750.2940.1340.0260.5160.0277

CCT (m)CC−0.1330.269−0.131−0.1080.1810.0190.043−0.1570.2070.178
SL-0.4330.1080.4410.5260.2820.9080.80.3520.2180.292

MD (dB)CC0.0820.078−0.131−0.4650.1170.050.0250.011−0.2870.153
SL-0.6290.6460.4410.00370.4910.7660.8820.9490.0840.366

PSD (dB)CC0.038−0.252−0.108−0.465−0.386−0.2790.0240.1380.152−0.524
SL-0.8230.1330.5260.00370.0180.09450.8890.4140.3690.0009

RNFL (m)CC0.1330.2960.1810.117−0.3860.6360.444−0.228−0.050.427
SL-0.4320.0750.2820.4910.0184<0.00010.0050.1750.7680.0083

GCC (m)CC0.0510.1770.0190.05−0.2790.6360.24−0.054−0.3790.361
SL-0.7620.2940.9080.7660.094<0.00010.1520.7530.02060.0283

Amplitude (V)CC−0.181−0.2510.0430.0250.0240.4440.240.285−0.32−0.037
SL-0.2840.1340.80.8820.8890.00590.1520.0870.05360.828

Phase ( rad)CC−0.128−0.364−0.1570.0110.138−0.228−0.0540.285−0.346−0.33
SL-0.4490.02680.3520.9490.4140.1750.7530.0870.03580.0461

CV_amp (%)CC0.1260.110.207−0.2870.152−0.05−0.379−0.32−0.3460.09
SL-0.4570.5160.2180.0840.3690.7680.02 0.0530.03580.597

CV_phase (%)CC0.1050.3620.1780.153−0.5240.4270.361−0.037−0.330.09
SL-0.5360.02770.2920.3680.00090.00830.0280.8280.04610.597

Intraocular pressure (IOP), central corneal thickness (CCT), mean deviation (MD), pattern standard deviation (PSD), retinal nerve fiber layer thickness (RNFL), ganglion cell complex (GCC), PERG amplitude, PERG phase, coefficient of variation PERG amplitude (CV_amp), and coefficient of variation PERG phase (CV_Phase).