Review Article
TTBK2: A Tau Protein Kinase beyond Tau Phosphorylation
Table 1
Potential homologs of the TTBK2 noncatalytic region identified by protein BLAST search.
| | Description | Alignment score | Query cover | value | Identity |
| | Search query: TTBK2 amino acid 281–448 | | | | | | Collagen alpha-1(XVIII) chain | 30.4 | 29% | 2 | 35% | | Aminopeptidase Q | 30 | 41% | 2.3 | 31% | | Search query: TTBK2 amino acid 449–1244 | | | | | | Hepatocyte cell adhesion molecule precursor | 33.9 | 9% | 1 | 33% | | Coiled-coil domain-containing protein 168 | 31.6 | 6% | 7.8 | 29% | | Neuroligin-3 | 31.6 | 7% | 8.1 | 33% | | Putative chondrosarcoma-associated gene 1 protein | 28.9 | 6% | 8.9 | 39% | | Neurogenic locus notch homolog protein 2 | 31.2 | 19% | 10 | 23% | | Coiled-coil domain-containing protein 146 | 30.8 | 7% | 11 | 33% | | Oxygen-regulated protein 1 | 30 | 20% | 25 | 26% | | Activated CDC42 kinase 1 | 29.6 | 5% | 31 | 42% | | Mucin-6 | 29.6 | 8% | 31 | 32% | | 72 kDa inositol polyphosphate 5-phosphatase | 29.3 | 11% | 32 | 31% | | FH2 domain-containing protein 1 | 29.6 | 6% | 33 | 38% | | Tumor necrosis factor receptor superfamily member 16 precursor | 28.9 | 9% | 41 | 24% | | SET domain-containing protein 5 | 28.9 | 10% | 49 | 30% | | Serine/threonine-protein kinase ATR | 28.5 | 18% | 61 | 23% | | Acyl-CoA-binding domain-containing protein 4 | 28.1 | 10% | 65 | 29% | | ADAMTS-like protein 4 | 28.5 | 4% | 67 | 36% | | Eukaryotic translation initiation factor 2-alpha kinase 3 | 28.5 | 12% | 68 | 28% | | Centrosomal protein of 97 kDa | 28.5 | 7% | 70 | 33% | | P protein | 28.5 | 9% | 72 | 34% | | Microtubule-actin cross-linking factor 1 | 28.1 | 10% | 80 | 27% | | Junctophilin-1 | 28.1 | 5% | 81 | 38% | | Sorbin and SH3 domain-containing protein 2 | 28.1 | 11% | 83 | 28% | | Neuron navigator 2 | 28.1 | 13% | 96 | 28% |
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