Research Article

Sublingual Immunotherapy with a Five-Grass Pollen Tablet in Adult Patients with Allergic Rhinitis: An Open, Prospective, Noninterventional, Multicenter Study

Table 1

Patient characteristics.

ParameterSafety analysis set
= 808

Age
 Mean ± SD [years]34.7 ± 12.3
 Median [years]33.0
 Range [years]18–82
Sex
 Male [ (%)]364 (45.0)
 Female [ (%)]444 (55.0)
Symptoms
 Allergic rhinitis [ (%)]804 (99.5)
 Severity in the grass pollen season 2008 [ (%)]
  Mild41 (5.1)
  Moderate323 (40.0)
  Severe433 (53.6)
 Allergic conjunctivitis [ (%)]625 (77.4)
 Severity in the grass pollen season 2008 [ (%)]
  Mild167 (20.7)
  Moderate301 (37.3)
  Severe232 (28.7)
 Allergic asthma [ (%)]189 (23.4)
Allergy history
 Mean ± SD duration since first occurrence [years]
  Allergic rhinitis10.2 ± 9.0
  Allergic conjunctivitis10.7 ± 9.2
  Allergic asthma9.2 ± 9.7
 History of immunotherapy [ (%)]
  No (first time immunotherapy)634 (78.5)
  Yes, completed146 (18.1)
  Yes, switch from an ongoing immunotherapy28 (3.5)
Concomitant allergies
 Yes [ (%)]580 (71.8)
 Concomitant allergies to [ (%)]
  Birch pollen394 (48.8)
  Other tree pollens332 (41.1)
  Weed pollens233 (28.8)
  House dust mites219 (27.1)
  Animal dander184 (22.8)
  Moulds71 (8.8)
Symptomatic medication
 Symptomatic medication intake during the grass pollen season 2008 [ (%)]679 (84.0)

: number of patients; %: percentage of patients.