Research Article
Transcriptomic and Immunohistochemical Profiling of SLC6A14 in Pancreatic Ductal Adenocarcinoma
Table 2
SLC6A14 IHC staining intensity.
| | | 0: none () | 1: weak () | 2: moderate () | 3: strong () | Total () | value |
| | Survival | | | | | | 0.1181 | | | 5 | 42 | 24 | 8 | 79 | | Events | 5 | 36 | 20 | 7 | 68 | Median survival
days | 633.0 (487.0–2532.0) | 733.0 (405.0–1247.0) | 595.0 (334.0–1281.0) | 366.0 (253.0–641.0) | 579.0 (419.0–962.0) | | 2 Yr survival rate | 40.0% (0.0%–82.9%) | 51.2% (35.9%–66.5%) | 45.8% (25.9%–65.8%) | 0.0% | 44.2% (33.1%–55.3%) | | Year 2 at risk | 2 | 21 | 11 | 0 | 34 | | Age of onset | | | | | | 0.1099 | | | 5 | 37 | 22 | 8 | 72 | | Mean (SD) | 73.0 (7.0) | 67.6 (10.6) | 66.5 (9.2) | 61.1 (9.0) | 66.9 (10.0) | | Median | 75.0 | 69.0 | 70.0 | 59.5 | 69.0 | | Q1, Q3 | 74.0, 76.0 | 61.0, 75.0 | 60.0, 75.0 | 54.0, 68.0 | 60.0, 75.0 | | Range | (61.0–79.0) | (37.0–85.0) | (48.0–76.0) | (50.0–76.0) | (37.0–85.0) | Median age of
onset | 75.0 (61.0–79.0) | 69.0 (64.0–73.0) | 70.0 (60.0–74.0) | 59.5 (50.0–69.0) | 69.0 (66.0–72.0) | 0.0978 | | Sex | | | | | | 0.2142 | | Missing | 0 | 8 | 4 | 3 | 15 | | Female | 1 (20.0%) | 25 (59.5%) | 10 (41.7%) | 3 (37.5%) | 39 (49.4%) | | Male | 4 (80.0%) | 17 (40.5%) | 14 (58.3%) | 5 (62.5%) | 40 (50.6%) | | Obesity | | | | | | 0.2358 | | Missing | 1 | 21 | 9 | 5 | 36 | | BMI < 30 | 2 (50.0%) | 24 (82.8%) | 17 (89.5%) | 4 (66.7%) | 47 (81.0%) | | BMI 30+ | 2 (50.0%) | 5 (17.2%) | 2 (10.5%) | 2 (33.3%) | 11 (19.0%) | | Diabetes self-reported | | | | | | 0.6592 | | Missing | 0 | 8 | 4 | 3 | 15 | | No DM | 5 (100.0%) | 33 (78.6%) | 18 (75.0%) | 6 (75.0%) | 62 (78.5%) | | DM | 0 (0.0%) | 9 (21.4%) | 6 (25.0%) | 2 (25.0%) | 17 (21.5%) | | Pancreatitis self-reported | | | | | | 0.8622 | | Missing | 0 | 8 | 4 | 3 | 15 | | No pancreatitis | 4 (80.0%) | 31 (73.8%) | 18 (75.0%) | 7 (87.5%) | 60 (75.9%) | | Pancreatitis | 1 (20.0%) | 11 (26.2%) | 6 (25.0%) | 1 (12.5%) | 19 (24.1%) | | Tumor grade | | | | | | 0.5917 | | 2 | 0 (0.0%) | 8 (16.0%) | 1 (3.6%) | 1 (9.1%) | 10 (10.6%) | | 3 | 4 (80.0%) | 31 (62.0%) | 20 (71.4%) | 6 (54.5%) | 61 (64.9%) | | 4 | 1 (20.0%) | 11 (22.0%) | 7 (25.0%) | 4 (36.4%) | 23 (24.5%) |
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